CLIV.—Benzoflavol (2 : 8-dihydroxy-5-phenyl-3 : 7-dimethylacridine)

5-Iodo-7-methyl-3-methyl­sulfinyl-2-phenyl-1-benzofuran

The title compound, C(16)H(13)IO(2)S, was prepared by the oxidation of 5-iodo-7-methyl-3-methyl-sulfanyl-2-phenyl-1-benzofuran with 3-chloro-peroxy-benzoic acid. The phenyl ring makes a dihedral angle of 27.17 (9)° with the plane of the benzofuran fragment, with the O atom and the methyl group of the methyl-sulfinyl substituent lying on opposite sides of this plane. The crystal structure exhibi...

5-Chloro-7-methyl-2-phenyl-3-phenyl­sulfinyl-1-benzofuran

In the title compound, C(21)H(15)ClO(2)S, the O atom and the phenyl group of the phenyl-sulfinyl substituent lie on opposite sides of the plane of the benzofuran fragment; the phenyl ring is almost perpendicular to this plane [82.24 (7)°]. The phenyl ring in the 2-position is rotated out of the benzofuran plane, making a dihedral angle of 11.50 (9)°. The crystal structure is stabilized by inter...

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27 A 3,204 bp full-length cDNA of bovine NALP9 was cloned and its genomic organisation was 28 analyzed. The 2,988 bp open reading frame covers 9 exons and encodes a deduced protein of 996 29 amino acids containing Pyrin, Nacht and leucine-rich repeat domains like the human NALP gene 30 family members. Mapping with the WGRH5000 panel and fluorescence in situ hybridisation 31 assigned NALP9 in cl...

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Synthesis, Reactions and Antioxidant Activity of 5-(3', 4'-dihydroxy-tetrahydrofuran-2'-yl)-2-methyl-3-carbohydrazide

In this manuscript, we describe the synthesis of the carbohydrazide 2. Acid-catalyzed condensation with several carbonyl compounds to afford the corresponding carbohydrazide derivatives 3-12. Their acetylation afforded the corresponding acetyl derivatives 13-22. Oxidative cyclization of O-acetyl derivatives 19-22 afforded the corresponding 1,3,4-oxadiazole derivatives 23-2...